Lipoic acid

CAS No. 1200-22-2

Lipoic acid( R)-(+)-α-Lipoic acid | alpha-Lipoic acid | R-(+)-Thioctic acid )

Catalog No. M10720 CAS No. 1200-22-2

A multifunction antioxidant that has growth promoting, anti-inflammatory, antioxidative, immunostimulatory, and hypocholesterolemic properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Lipoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    A multifunction antioxidant that has growth promoting, anti-inflammatory, antioxidative, immunostimulatory, and hypocholesterolemic properties.
  • Description
    A multifunction antioxidant that has growth promoting, anti-inflammatory, antioxidative, immunostimulatory, and hypocholesterolemic properties.Pain Phase 3 Clinical(In Vitro):Lipoic acid ((R)-(+)-α-Lipoic acid) is the form biosynthesized in humans which is essential for aerobic metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) is the nutritionally and therapeutically preferred form due to its "vitamin-like" role in metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) and S-(-)-α-Lipoic acid) constitute the racemic mixture Lipoic acid. Only the Lipoic acid ((R)-(+)-α-Lipoic acid) exists in nature and is an essential cofactor of four mitochondrial enzyme complexes. Lipoic acid ((R)-(+)-α-Lipoic acid) has been suggested to be nutritionally and therapeutically preferred form as antioxidant.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    R)-(+)-α-Lipoic acid | alpha-Lipoic acid | R-(+)-Thioctic acid
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB
  • Research Area
    Neurological Disease
  • Indication
    Pain

Chemical Information

  • CAS Number
    1200-22-2
  • Formula Weight
    206.3256
  • Molecular Formula
    C8H14O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(O)CCCC[C@@H]1CCSS1
  • Chemical Name
    1,2-Dithiolane-3-pentanoic acid, (3R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kuban-Jankowska A, et al. Anticancer Res. 2017 Jun;37(6):2893-2898. 2. Tibullo D, et al. Mol Neurobiol. 2017 May 11. 3. Cho HS, et al. Sci Rep. 2017 Apr 5;7:46065.
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